The presented study explores the influence of antibacterial activity and biocompatibility of antibacterial drugs on titanium nanotubes. The presenter, Morteza Khodaei Vaighan, is a bachelor’s student from the Faculty of Materials Science and Engineering at Sharif University of Technology. The aim of this research is to enhance the biocompatibility and antibacterial capabilities of implant surfaces to prevent bacterial infections. Results demonstrate that by effectively controlling the structural parameters of titanium nanotubes, it’s possible to produce implant surfaces that simultaneously enhance biocompatibility and antibacterial activity. Among the three crystalline phases—Anatase, Rutile, and Amorphous Titanium Dioxide—Anatase nanotubes exhibit the highest antibacterial activity. Clinical applications involving Staphylococcus aureus are used to assess the antimicrobial effects of titanium dioxide.
The experiments showcase that titanium nanotubes have the potential to significantly inhibit the growth of Staphylococcus aureus, highlighting their antibacterial properties. Laboratory assessments of biocompatibility indicate that fibroblast cells exhibit diameter-dependent behavior on grown titanium nanotubes. The research is crucial due to the widespread use of biomaterials within the human body, particularly in implants, where bacterial infections can undermine the mechanical properties, corrosion resistance, biocompatibility, and overall function of titanium materials. Therefore, creating implant surfaces with intrinsic antibacterial properties is essential.
To achieve this, the researchers utilize anodization to prepare titanium nanotubes and deposit silver ions onto their surfaces. The silver ions contribute to the antibacterial activity of the nanotubes. The antibacterial activity is evaluated through tests involving Staphylococcus aureus and Escherichia coli. Scanning electron microscopy (SEM), X-ray diffraction (XRD), and transmission electron microscopy (TEM) are employed to analyze the morphology and characteristics of the titanium nanotubes. The study provides valuable insights into enhancing the biocompatibility and antibacterial properties of titanium nanotube-based implant surfaces, thereby contributing to the advancement of biomaterial applications.
The files available for your reference can be accessed within this section of the website.